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. 2009 Oct 14;82(3):516–527. doi: 10.1095/biolreprod.109.080374

FIG. 6.

FIG. 6.

Alterations in the expression and localization of claudin11, occludin, and ZO1 in the seminiferous epithelium are observed by immunohistochemical analysis. Twenty-eight-day-old C57BL/6J mice are pretreated with SB-3CT (0 and 25 mg/kg) for 6 h and then posttreated with 1 g/kg of MEHP for another 12 h. Control (A–C); MEHP treatment only (D–F); 25 mg/kg of SB-3CT pretreatment with MEHP posttreatment (G–I). a–i) The magnified view of the BTB (boxed area). Testis cross sections show that claudin11, occludin, and ZO1 strongly express along the BTB. The expression of both claudin11 and occludin is decreased after MEHP exposure, while they are increased in 25 mg/kg SB-3CT-pretread mice testes. The expression of occludin in the adluminal compartment is indicated by an arrow head. The expression of ZO1 is not significantly influenced by MEHP or SB-3CT treatment. Bar = 50 μm.