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. 1999 Oct 16;319(7216):1027–1030. doi: 10.1136/bmj.319.7216.1027

Table 2.

Odds ratios (95% confidence interval) of risk factors for breast cancer derived from univariate analysis entered into multivariate analysis

Risk factor Odds ratio (95% CI) P value
Age (years) v 40-49 years:
 50-59 1.79 (0.91 to 3.53) 0.000*
 60-69 10.68 (5.12 to 22.30) 0.000*
 70-79 16.40 (7.26 to 37.03) 0.000*
History of benign breast lumps 0.19 (0.10 to 0.35) 0.000*
Months breast feeding v no breast feeding:
 0.5-8 1.56 (0.88 to 2.77) 0.124*
 >8 1.28 (0.74 to 2.22) 0.384
Menopausal status v premenopausal:
 Perimenopausal 0.99 (0.39 to 2.48) 0.977
 Postmenopausal 3.34 (1.76 to 6.35) 0.000*
Age at menopause v premenopausal:
 28-40 1.54 (0.59 to 3.99) 0.377
 41-49 2.81 (1.47 to 5.37) 0.002*
 >50  5.82 (2.85 to 11.85) 0.000*
Age at hysterectomy v no hysterectomy:
 27-42 0.39 (0.16 to 0.98) 0.045*
 >43 1.72 (0.87 to 3.37) 0.117*
Ever had hormone replacement therapy 0.71 (0.43 to 1.19) 0.194*
Years of hormone replacement therapy v never had hormone replacement therapy:
 0.2-4.5 0.64 (0.32 to 1.27) 0.203*
 5.0-24.0 0.79 (0.41 to 1.50) 0.470
Past use of oral contraceptive pill 0.39 (0.24 to 0.62) 0.000*
No of years taking oral contraceptive pill v never taken oral contraceptive pill:
 0.25-6.5 0.35 (0.19 to 0.62) 0.000*
 7.0-22.0 0.44 (0.24 to 0.79) 0.007*
Body mass index (kg/m2) v 17.0-22.0 kg/m2:
 22.1-24.2 0.67 (0.50 to 0.97) 0.008*
 24.3-47.0 1.46 (1.08 to 1.97) 0.013*
Units of alcohol/week v 0 units/week:
 1-4 0.57 (0.31 to 1.04) 0.068*
 5-9 0.60 (0.31 to 1.15) 0.124*
 ⩾10 0.78 (0.40 to 1.49) 0.448 
*

P<0.25; variable entered into multivariate analysis.