Table 2.
Risk factor | Odds ratio (95% CI) | P value |
---|---|---|
Age (years) v 40-49 years: | ||
50-59 | 1.79 (0.91 to 3.53) | 0.000* |
60-69 | 10.68 (5.12 to 22.30) | 0.000* |
70-79 | 16.40 (7.26 to 37.03) | 0.000* |
History of benign breast lumps | 0.19 (0.10 to 0.35) | 0.000* |
Months breast feeding v no breast feeding: | ||
0.5-8 | 1.56 (0.88 to 2.77) | 0.124* |
>8 | 1.28 (0.74 to 2.22) | 0.384 |
Menopausal status v premenopausal: | ||
Perimenopausal | 0.99 (0.39 to 2.48) | 0.977 |
Postmenopausal | 3.34 (1.76 to 6.35) | 0.000* |
Age at menopause v premenopausal: | ||
28-40 | 1.54 (0.59 to 3.99) | 0.377 |
41-49 | 2.81 (1.47 to 5.37) | 0.002* |
>50 | 5.82 (2.85 to 11.85) | 0.000* |
Age at hysterectomy v no hysterectomy: | ||
27-42 | 0.39 (0.16 to 0.98) | 0.045* |
>43 | 1.72 (0.87 to 3.37) | 0.117* |
Ever had hormone replacement therapy | 0.71 (0.43 to 1.19) | 0.194* |
Years of hormone replacement therapy v never had hormone replacement therapy: | ||
0.2-4.5 | 0.64 (0.32 to 1.27) | 0.203* |
5.0-24.0 | 0.79 (0.41 to 1.50) | 0.470 |
Past use of oral contraceptive pill | 0.39 (0.24 to 0.62) | 0.000* |
No of years taking oral contraceptive pill v never taken oral contraceptive pill: | ||
0.25-6.5 | 0.35 (0.19 to 0.62) | 0.000* |
7.0-22.0 | 0.44 (0.24 to 0.79) | 0.007* |
Body mass index (kg/m2) v 17.0-22.0 kg/m2: | ||
22.1-24.2 | 0.67 (0.50 to 0.97) | 0.008* |
24.3-47.0 | 1.46 (1.08 to 1.97) | 0.013* |
Units of alcohol/week v 0 units/week: | ||
1-4 | 0.57 (0.31 to 1.04) | 0.068* |
5-9 | 0.60 (0.31 to 1.15) | 0.124* |
⩾10 | 0.78 (0.40 to 1.49) | 0.448 |
P<0.25; variable entered into multivariate analysis.