Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Feb 22;5(2):e9240. doi: 10.1371/journal.pone.0009240

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Pan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) The within module degree -score of each neuron in the empirical neuronal network is shown against the corresponding participation coefficient . The within module degree measures the connectivity of a node to other nodes within its own module, while the participation coefficient measures its connectivity with neurons in the entire network. (B) The corresponding result for a randomized version of the C. elegans network where the degree of each neuron is kept unchanged is also shown. Neurons belonging to the different regions in the space are categorised as: (gray) R1: “ultraperipheral nodes”, i.e., nodes with all their links within their module, (blue) R2: “peripheral nodes”, i.e., nodes with most links within their module, (pink) R3: “nonhub connector nodes”, i.e., nodes with many links to other modules, (green) R4: “nonhub kinless nodes”, i.e., nodes with links homogeneously distributed among all modules, (yellow) R5: “provincial hubs”, i.e., hub nodes with the vast majority of links within their module, (red) R6: “connector hubs”, i.e., hubs with many links to most of the other modules, and (white) R7: “global hubs”, i.e., hubs with links homogeneously distributed among all modules. The neurons occurring as connector hubs are identified in the figure. Most of these neurons occur in different functional circuits indicating the close relation between functional importance and connectivity pattern of individual neurons. In addition, the neurons AVKL and SMBVL which are predicted to be functionally important are separately marked.

Inline graphic — (A) The within module degree -score of each neuron in the empirical neuronal network is shown against the corresponding participation coefficient . The within module degree measures the connectivity of a node to other nodes within its own module, while the participation coefficient measures its connectivity with neurons in the entire network. (B) The corresponding result for a randomized version of the C. elegans network where the degree of each neuron is kept unchanged is also shown. Neurons belonging to the different regions in the space are categorised as: (gray) R1: “ultraperipheral nodes”, i.e., nodes with all their links within their module, (blue) R2: “peripheral nodes”, i.e., nodes with most links within their module, (pink) R3: “nonhub connector nodes”, i.e., nodes with many links to other modules, (green) R4: “nonhub kinless nodes”, i.e., nodes with links homogeneously distributed among all modules, (yellow) R5: “provincial hubs”, i.e., hub nodes with the vast majority of links within their module, (red) R6: “connector hubs”, i.e., hubs with many links to most of the other modules, and (white) R7: “global hubs”, i.e., hubs with links homogeneously distributed among all modules. The neurons occurring as connector hubs are identified in the figure. Most of these neurons occur in different functional circuits indicating the close relation between functional importance and connectivity pattern of individual neurons. In addition, the neurons AVKL and SMBVL which are predicted to be functionally important are separately marked.