Table I.
CHO ERCC3 mutations
| Cell line | Type of change | cDNA | Protein (1-letter) (change deduced only) | Type of mutation | Protein truncated by |
| 27-1a | Substitution | c.1075A > G | K359E | Missense | 0 AA |
| MMC-2a | Substitution | c.2215C > T | Q739X | Nonsense | 44 AA |
| UV23 | Substitution | c.2218-2A > G | (A740_S748>LfsX7) | Splicing | 37 AA |
| Frameshift | |||||
| UV24a | Substitution | c.(1144T > C; 2215C > T) | (S382P; Q739X) | Missense | 44 AA |
| Nonsense | |||||
| UV68 | Substitution | c.1411G > T | V471F | Missense | 0 AA |
| UV78 UV179 | Substitution | c.2191G > T | G731X | Nonsense | 52 AA |
| UV113 | Insertion | c.2218-2219insG | A740GfsX16 | Frameshift | 28 AA |
| UV218 | Substitution | c.(2225G > C;2227-2228insC) | (R742P; R743PfsX13) | Missense | 28 AA |
| Insertion | Frameshift |
a
Mutations were identified in (17). AA, amino acids.