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Body weight change (A), daily food intake (B), cumulative food intake (C), rectal temperature (D) and brown adipose tissue fatty acid oxidation (FAO; E) in mice treated with the MCH1 receptor antagonist (MCH1 ant) or pair-fed mice. Data are mean ± standard error (n= 10–13). *P < 0.05, **P < 0.01 versus vehicle-treated/ad lib.-fed group, ##P < 0.01 versus vehicle/pair-fed group. MCH, melanin-concentrating hormone.
