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. 2009 Dec 10;159(2):374–383. doi: 10.1111/j.1476-5381.2009.00536.x

Table 3.

Tissue weights, TG contents and plasma parameters in MCH1 receptor antagonist-treated or pair-fed DIO mice

	Vehicle/ad libitum-fed	MCH1 ant.	Vehicle/pair-fed
Mesenteric fat (g)	1.27 ± 0.09	0.39 ± 0.04^**,^#	0.75 ± 0.04^**
Body fat mass (g)	21.4 ± 0.9	10.5 ± 0.8^**,^#	15.8 ± 0.8^**
Body lean mass (g)	27.8 ± 0.5	26.4 ± 0.3*	26.8 ± 0.3
Liver weight (g)	2.1 ± 0.1	1.6 ± 0.1^**	1.5 ± 0.1^**
Liver TG (mg·g⁻¹ tissue)	74.2 ± 8.0	29.5 ± 3.2^**	37.2 ± 3.0^**
Glucose (mg·L⁻¹)	2102 ± 64	1707 ± 74^**	1750 ± 55^**
Insulin (ng·mL⁻¹)	8.9 ± 1.0	3.0 ± 0.3^**	4.0 ± 0.4^**
Leptin (ng·mL⁻¹)	62.4 ± 3.6	17.1 ± 1.9^**,^#	34.5 ± 2.2^**
TG (mg·L⁻¹)	170 ± 10	170 ± 20	150 ± 10
Total cholesterol (mg·L⁻¹)	1740 ± 400	1160 ± 80^**	1280 ± 60^**
FFAs (µEq·L⁻¹)	561 ± 40	459 ± 20^**	501 ± 21

Data are means ± standard error (n= 10–13).

^*

P < 0.05;

^**

P < 0.01 versus vehicle/ad libitum-fed group;

^#

P < 0.01 versus vehicle/pair-fed group.

DIO, diet-induced obesity; FFAs, free fatty acids; TG, triglycerides.