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Overproduction of squalene in a quadruple mutant dga1Δlro1Δare1Δare2Δ does not induce lipid particle formation. Wild type (A), hem1Δ (B), QM (C), and QMhem1Δ (D) were grown to the stationary phase and then processed and inspected by electron microscopy as described under “Experimental Procedures.” Bar, 1 μm. LP, lipid particle.
