FIGURE 1.

Bi-1 expression is decreased in mouse models of obesity and diabetes. a, shown is relative expression of Bi-1 mRNA in the liver, skeletal muscle (SM), and white adipose tissue (WAT) from diabetic (db/db) (filled gray bars), obese (ob/ob) (filled black bars), and age-and sex-matched lean control mice (open bars) (mean ± S.E. of 15 animals in each group). Statistical significance was determined by t test and is denoted by asterisks (* p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001). b, shown is relative expression of Bi-1 mRNA in the liver and skeletal muscle from mice HFD (n = 12) (gray bars)- and ND (n = 8) (white bars)-fed C57Bl/6 mice (mean ± S.E. is shown of each group). Statistical significance was determined by t test and is denoted by asterisks (***, p ≤ 0.001).