Figure 5. Latency and duration of activity in myenteric neurons at the onset of CMMCs.

A, the latency of onset of excited neurons following an anal mucosal stimulus (61 neurons; n= 4). B, the duration of Ca²⁺ transients in neurons (♦) and muscle (○) following evoked CMMCs (n= 6). C, the activation of excited neurons (upper bars) and inhibited neurons (lower bars) relative to the first rapid Ca²⁺ transient in the muscle (0 s) following an evoked CMMC (85 neurons, n= 6). Note that a number of neurons fired before the onset of the muscle, and that the neurons that ceased firing often occurred later during the CMMC.