Table 1.

Functional Annotation Clusters Identified by the DAVID Functional Annotation Clustering Tool¹

Annotation Cluster	Enrichment Score	Functional Annotation	# of genes
1	12.34	Extracellular Region	47
		Secreted	43
2	10.10	Signal	65
		Secreted	43
		Signal Peptide	63
		Glycoprotein	64
3	8.46	Developmental Process	66
		Anatomical Structure Development	50
4	6.61	Extracellular Region Part	32
		Proteinaceous Extacellular Matrix	15
		Extracellular Matrix	15
5	6.24	Cell Proliferation	27
6	5.77	Response To External Stimulus	25
		Response To Wounding	19
		Response To Stress	29
7	5.66	Tissue Development	16
8	5.19	Receptor Binding	23
		Cytokine Activity	13
9	5.07	Positive Regulation of Biol. Process	29
10	4.51	Locomotory Behavior	12
11	4.47	Neg. Regulation of Biol. Process	30
12	4.0	Neg. Regulation of Biol. Process	30
		Cellular Developmental Process	38
		Cell-Cell Signaling	17
		Cell Death	21
		Apoptosis	20
13	3.98	Cell Adhesion	21
14	3.94	Cytokine Activity	13
		Inflammatory Response	13
15	2.56	Epidermolysis bullosa	4
16	2.53	Growth Factor Binding	4
		Regulation of Cell Growth	8
17	2.48	Cell Motility	13
18	2.16	Leukocyte Migration	4
		Cell Migration	8
19	2.14	Regulation of Prog. Through Cell Cycle	14
		Regulation of Cell Cycle	14
		Cell Cycle Process	16
20	2.06	EGF-like Region	12

¹Genes from Tables 1 and 2 were analyzed using the DAVID Functional Annotation Clustering Tool (http://david.abcc.ncifcrf.gov). The top 20 annotation clusters are shown.