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Fig. 3.

Fig. 3.

Venn diagram of proteomic results. A: the number of proteins identified in the NE, NP, and cytoplasmic fractions (Cyto) with an estimated single-peptide false discovery rate specified as 2% or less. A total of 3,531 proteins were identified in one or more of the 3 fractions. B: the number of proteins identified in the NE fraction by each searching algorithm (SEQUEST, InsPecT, and OMSSA). Intersections between each circle show the number of proteins identified by a combination of search algorithms. C: the number of proteins identified in the NE fraction using 2 different proteases (trypsin and chymotrypsin).