Fig. 5.
Transcription factor binding site analysis. The 1,000 bp 5′-flanking region and 1st intron of the Aqp2 and Aqp3 genes of human, rat, and mouse were analyzed for conserved transcription factor binding sites (TFBS) using Genomatix database and software suite. This figure represents only Rat Aqp2 and Aqp3 genes. Conserved TFBS were found in the 1,000 bp 5′-flanking region of the Aqp2 and Aqp3 genes and the 1st intron of the Aqp2, however, no conserved TFBS were found in the 1st intron of the Aqp3 gene. Transcription factors identified in this study that potentially bind to these TFBS are shown above each TFBS. Abbreviations for Genomatix TFBS family name: V$SF1F = Vertebrate steroidogenic factor; V$NFAT = Nuclear factor of activated T-cells; V$FKHD = Fork head domain factors; V$ETSF = Human and murine ETS1 factors; V$RXRF = RXR heterodimer binding sites; V$AP2F = Activator protein 2; V$CREB = cAMP-responsive element binding proteins; V$GATA = GATA binding factors; V$SRFF = Serum response element binding factor; V$HOXF = Paralog hox genes 1–8 from the four hox clusters A, B, C, D; V$EBOX = E-box binding factors; V$EGRF = EGR/nerve growth factor induced protein C & related factors; V$MYT1 = MYT1 C2HC zinc finger protein; V$KLFS = Krueppel like transcription factors; V$CP2F = CP2-erythrocyte Factor related to drosophila Elf1; V$CEBP = Ccaat/Enhancer Binding Protein; V$PARF = PAR/bZIP family; V$NR2F = Nuclear receptor subfamily 2 factors; V$HAND = Twist subfamily of class B bHLH transcription factors; V$GREF = Glucocorticoid responsive and related elements; V$MAZF = Myc associated zinc fingers; V$ZBPF = Zinc binding protein factors; and V$SP1F = GC-Box factors SP1/GC.