Figure 1. Reduction of AMPKα2 expression induces ER stress in endothelial cells.
A&B. Western blot analysis of AMPKα2 in HUVEC. The blot is representative of at least three blots from three independent experiments; ♣p<0.05, AMPKα1 or α2 or AMPKα siRNA vs. control siRNA, respectively; #p<0.05, AMPKα2 siRNA vs. AMPKα1 siRNA; †p<0.05, AMPKα siRNA vs. AMPKα1 or α2 siRNA. n=4. C&D. Genetic inhibition of AMPKα2 induces ER stress in HUVEC. ♣p<0.05 vs. control siRNA; #p<0.05 vs. AMPKα1 siRNA, †p<0.05 vs. AMPKα1 or AMPK α2 siRNA; n=4.