TABLE 4.

Genes associated with the hematological system that are differentially expressed in strain 927-infected mice and strain 247-infected mice

Gene	Product	Location	Type	FCb
Achea	Acetylcholinesterase	Plasma membrane	Enzyme	−2.1
Aicdaa	Activation-induced cytidine deaminase	Cytoplasm	Enzyme	−1.9
ApoEa	Apolipoprotein E	Extracellular space	Transporter	2.1
Art2A	ADP-ribosyltransferase 2a	Extracellular space	Enzyme	−1.9
C3ar1	Complement component 3a receptor 1	Plasma membrane	G-protein-coupled receptor	1.9
C5ar1	Complement component 5a receptor 1	Plasma membrane	G-protein-coupled receptor	1.8
Ccl3	Chemokine (C-C motif) ligand 3	Extracellular space	Cytokine	2.2
Ccl8	Chemokine (C-C motif) ligand 8	Extracellular space	Cytokine	2.2
Ccr6	Chemokine (C-C motif) receptor 6	Plasma membrane	G-protein-coupled receptor	−2
CD14	CD14 molecule	Plasma membrane	Transmembrane receptor	3.7
CD22a	CD22 molecule	Plasma membrane	Other	−2.3
CD71a	CD71 molecule	Plasma membrane	Transporter	−2.3
CD80	CD80 molecule	Plasma membrane	Transmembrane receptor	2.4
CD163	CD163 molecule	Plasma membrane	Transmembrane receptor	1.9
Cr2a	Complement component receptor 2	Plasma membrane	Transmembrane receptor	−3.0
Ctla4	Cytotoxic T-lymphocyte-associated protein 4	Plasma membrane	Other	4.4
Ctsl2	Cathepsin L2	Cytoplasm	Peptidase	2.4
Cxcl3	Chemokine (C-X-C motif) ligand 3	Extracellular space	Cytokine	6.1
Cxcr7	Chemokine (C-X-C motif) receptor 7	Plasma membrane	G-protein-coupled receptor	3.6
Darca	Duffy blood group, chemokine receptor	Plasma membrane	G-protein-coupled receptor	−3.8
Dusp1	Dual-specificity phosphatase 1	Nucleus	Phosphatase	2.8
Epb42a	Erythrocyte membrane protein band 4.2	Plasma membrane	Transporter	−4.7
Epb49a	Erythrocyte membrane protein band 4.9 (dematin)	Plasma membrane	Other	−3.2
F7	Coagulation factor VII (serum prothrombin conversion accelerator)	Plasma membrane	Peptidase	2.8
Fcgr2b	Fc fragment of immunoglobulin G, low-affinity IIb, receptor (CD32)	Plasma membrane	Transmembrane receptor	2.3
Fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	Nucleus	Transcription regulator	5.2
Fprl1	Formyl peptide receptor 2	Plasma membrane	G-protein-coupled receptor	2.0
Gna13	Guanine nucleotide binding protein (G protein), alpha 13	Plasma membrane	Enzyme	2.8
Igh-1A	Immunoglobulin heavy chain 1a (serum immunoglobulin G2a)	Extracellular space	Other	1.9
IL1rl1	IL-1 receptor-like 1	Plasma membrane	Transmembrane receptor	2.1
IL1rN	IL-1 receptor antagonist	Extracellular space	Cytokine	2.0
IL4Iia	IL-4-induced 1	Cytoplasm	Enzyme	−2.0
Klf1a	Krüppel-like factor 1 (erythroid)	Nucleus	Transcription regulator	−4.1
Lcn2	Lipocalin 2	Extracellular space	Transporter	1.9
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	Plasma membrane	Other	2.0

^aGene upregulated in strain 247-infected mice compared to strain 927-infected mice.

^bFC, fold change.