TABLE 3.
Resistance of Y. pestis KIM5 and KIM5 ΔpgmA to various human antimicrobial peptides
| Strain (temp) | MIC (μg/ml) of:a |
||||
|---|---|---|---|---|---|
| α-Defensin-1 | α-Defensin-3 | β-Defensin-1 | β-Defensin-2 | LL-37 | |
| KIM5 (28°C) | >64 | >64 | >64 | >64 | 32 |
| KIM5 ΔpgmA (28°C) | >64 | >64 | >64 | >64 | 32 |
| K. rhizophila ATCC 9341 (28°C) | 32 | 64 | >64 | 32 | 4 |
| KIM5 (37°C) | >64 | >64 | >64 | >64 | >64 |
| KIM5 ΔpgmA (37°C) | >64 | >64 | >64 | >64 | >64 |
Results are based on two independent experiments that gave identical MICs.