TABLE 2.
Responder frequencies for the esx locus proteins
| Protein source | Responder frequency (%) fora: |
|
|---|---|---|
| CFP-10-like protein | ESAT-6-like protein | |
| Complete esx loci | ||
| ESX-1 locus | 70 (Rv3874)b | 80 (Rv3875)b |
| ESX-2 locus | 30 (Rv3891c) | 39 (Rv3890c) |
| ESX-3 locus | 94 (Rv0287)c | 75 (Rv0288)d |
| ESX-4 locus | 43 (Rv3445c) | 57 (Rv3444c) |
| ESX-5 locus | 61 (Rv1792) | 0 (Rv1793) |
| Mean ± SEM | 60 ± 11 | 50 ± 14 |
| Regions of partial esx loci | ||
| Region 1 | 39 (Rv3905c) | 30 (Rv3904c) |
| Region 2 | 61 (Rv3020c) | 16 (3019c)e |
| Region 3 | NAf | 57 (Rv2346c) |
| Region 4 | 48 (Rv1198) | 61 (Rv1197) |
| Region 5 | 65 (Rv1038c) | 48 (Rv1037c) |
| Region 6 | NAf | NAf |
| Mean ± SEM | 53 ± 6 | 42 ± 8 |
a
Designations of M. tuberculosis H37Rv proteins are given in parentheses.
b
Information is from reference 33 and unpublished data.
c
Information is from reference 19.
d
Information is from reference 12 and H. M. Vordermeier, unpublished data.
e
Information is from Vordermeier, unpublished.
f
NA, not applicable. Rv2347c, Rv3620c, and Rv3619c are encoded by regions deleted in M. bovis.