TABLE 1.
Genotype frequencies and adjusted odds ratios for the TLR9 −1237T/C polymorphism
| Subject genotype |
H. pylori-positive subjects |
H. pylori-negative subjects |
Population controls (n = 100) | |||
|---|---|---|---|---|---|---|
| Low acid/atrophy (n = 51) | Normal/high acid (n = 66) | OR (95% CI)a | No. of subjects (n = 51) | OR (95% CI)b | ||
| T/T | 25 | 52 | 1.0 | 35 | 1.0 | 75 |
| T/C | 26 | 14 | 3.9 (1.7-8.6) | 15 | 0.9 (0.2-3.8) | 22 |
| C/C | 0 | 0 | 1 | 3 | ||
a
The OR (and Cornfield 95% confidence interval) for low-acid versus normal/high-acid conditions, adjusted for age and within-family sampling, is given. ORs were calculated for the carriage of “C” (TT versus T/C + C/C).
b
The OR for H. pylori-positive versus H. pylori-negative subjects is given.