FIG. 2.

Reactivity of human sera to overlapping DBPII peptide array. The average OD values for the peptides with highly inhibitory sera (n = 4) and noninhibitory sera (n = 22) are indicated by red and green lines, respectively, while the gray line indicates the average OD values for the nonexposed North American sera (n = 6) that served as a background control. An epitope is considered a B-cell epitope when the difference in OD value between the highly inhibitory sera (HI) and the noninhibitory sera (NI) is greater than the mean plus 2 standard deviations of the values for the North American control sera.