FIG. 1.
In vitro dose-response curves for posaconazole against Fusarium solani clinical isolate 95-2478 at 1 × 104 conidia/ml (A and B) and 1 × 105 conidia/ml (C and D) after 24 h (A and C) and 48 h (B and D) of incubation. Curves were generated by fitting XTT absorbance data to a four-parameter inhibitory sigmoid model. The concentrations resulting in 50% and 90% inhibition of growth (IC50 and IC90) and coefficients of determination (R2) are reported.