TABLE 4.
Probability of clinical success in the presence of one unfavorable factor
| Factora | Probability |
|---|---|
| Wt, ≥94 kg | 0.968 |
| Presence of P. aeruginosa in baseline cultures | 0.950 |
| APACHE II score, ≥13 | 0.947 |
| Hispanic race | 0.941 |
| Diagnosis of abscess, peritonitis due to perforation, or other | 0.938 |
| AUC/MIC ratio, <3.1 | 0.855 |
a
The remaining factors were set to the conditions favoring clinical response. The following conditions represented the most favorable for optimizing clinical response: weight of <94 kg, absence of P. aeruginosa in baseline cultures, APACHE II score of <13, non-Hispanic race, diagnosis of complicated appendicitis or cholecystitis, and an AUC/MIC ratio of ≥3.1.