TABLE 2.
Univariate analysis for association with microbiological response
| Variable | Microbiological failure (n = 24) | Microbiological success (n = 32) | P value |
|---|---|---|---|
| Mean (SD) age (yr) | 59.4 (22.4) | 62.0 (17.9) | 0.624 |
| Mean (SD) APACHE II score | 14.6 (6.2) | 13.2 (7.6) | 0.443 |
| Mean (SD) CLCR (ml/min) | 110 (57) | 91.3 (50.5) | 0.199 |
| No. (%) of patients with the following comorbidities: | |||
| Diabetes | 9 (37.5) | 11 (34.4) | 0.968 |
| Cardiovascular disease | 12 (50) | 10 (31.3) | 0.252 |
| Chronic renal failure | 4 (16.7) | 7 (21.9) | 0.741 |
| Immunosuppression | 0 (0) | 4 (12.5) | 0.127 |
| No. (%) of patients with infection at the following site: | |||
| Respiratory | 20 (83.3) | 17 (53.1) | 0.038 |
| Bacteremia | 2 (8.3) | 3 (9.4) | 1.000 |
| Skin and skin structure | 2 (8.3) | 12 (37.5) | 0.029 |
| No. (%) of patients receiving combination therapy | 13 (54.2) | 8 (25.0) | 0.051 |