TABLE 2.
Viral kinetic parameters for telbivudine and entecavir
| Parameter | Value for treatment group |
P | |
|---|---|---|---|
| Telbivudinea (n = 23) | Entecavir (n = 21) | ||
| Mean viral clearance rate ± SD (1/day) | 0.809 ± 0.390 | 1.002 ± 0.082 | 0.314 |
| Mean rate of infected cell loss ± SD (1/day) | 0.075 ± 0.023 | 0.071 ± 0.028 | 0.627 |
| Mean efficiency factor (%) of blocking virus production ± SD | 99.1 ± 1.3 | 99.2 ± 0.9 | 0.736 |
a
The value for 1 patient in the telbivudine group was excluded, as this patient showed a deviation from the biphasic pattern in viral kinetic modeling.