TABLE 3.
Incidence of adverse events
| Adverse eventa | No. (%) of adverse events for group |
|
|---|---|---|
| Telbivudine (n = 23) | Entecavir (n = 21) | |
| ALT level increased | 3 (13.0) | 1 (4.8) |
| Upper respiratory tract infection | 1 (4.3) | 2 (9.5) |
| Chest discomfort | 1 (4.3) | 1 (4.8) |
| Abdominal discomfort | 1 (4.3) | 0 (0.0) |
| Abdominal pain, upper | 1 (4.3) | 0 (0.0) |
| AST level increased | 1 (4.3) | 0 (0.0) |
| Conjunctival hyperemia | 1 (4.3) | 0 (0.0) |
| Dyspnea | 1 (4.3) | 0 (0.0) |
| Gingival bleeding | 1 (4.3) | 0 (0.0) |
| Hypophosphatemia | 1 (4.3) | 0 (0.0) |
| Myalgia | 1 (4.3) | 0 (0.0) |
| Neutropenia | 1 (4.3) | 0 (0.0) |
| Thrombocytopenia | 1 (4.3) | 0 (0.0) |
| Blood CK level increased | 0 (0.0) | 3 (14.3) |
| Nausea | 0 (0.0) | 2 (9.5) |
| Facial edema | 0 (0.0) | 1 (4.8) |
| Headache | 0 (0.0) | 1 (4.8) |
| Hordeolum | 0 (0.0) | 1 (4.8) |
| Insomnia | 0 (0.0) | 1 (4.8) |
| Myringitis | 0 (0.0) | 1 (4.8) |
| Nasopharyngitis | 0 (0.0) | 1 (4.8) |
| Proteinuria | 0 (0.0) | 1 (4.8) |
| Vaginal hemorrhage | 0 (0.0) | 1 (4.8) |
| Vomiting | 0 (0.0) | 1 (4.8) |
| Total | 9 (39.1) | 13 (61.9) |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase.