TABLE 3.
PBP mutations in S. uberis isolates naturally presenting decreased susceptibility to penicillin
| Isolate | Origin | MIC (μg/ml) | Mutation(s) |
||
|---|---|---|---|---|---|
| PBP1A | PBP2B | PBP2X | |||
| ALP8092 | Switzerland | 0.25 | G386R | —a | E381K/Q554E |
| ALP 8144 | Switzerland | 0.25 | — | — | E381K/Q554E |
| BL246 | Switzerland | 0.25 | — | N366I/T402I | E381K/Q554E |
| 1.11 | Holland | 0.25 | G386R | T593A | E381K/Q554E |
| 20568 | France | 0.5 | G386R | N366I/T402I/V570A/P575S | E381K/Q554E |
| 20592 | France | 0.5 | — | — | E381K/Q554E |
| 20618 | France | 0.25 | G386R | — | E381K/Q554E |
a
—, no detected mutation.