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Proportions of N. meningitidis isolates by penicillin MIC in Ontario from 2000 to 2006. No difference was seen over time in either the proportion of isolates corresponding to each MIC or the geometric mean MIC, as described in the text. A nonsignificant decrease in the proportion of isolates for which the penicillin MIC was 0.25 μg/ml (from 10.94 to 4.35% [P = 0.21]) between 2000 and 2006 was observed.
