TABLE 3.
MOI dependency of AIC246
| MOIa | EC50b (μM) |
|
|---|---|---|
| AIC246 | Ganciclovir | |
| 0.003 | 0.0013 ± 0.0004 (4) | 0.99 ± 0.58 (5) |
| 0.01 | 0.0015 ± 0.0004 (2) | 0.68 ± 0.30 (4) |
| 0.03 | 0.0029 ± 0.0012 (5) | 1.74 ± 1.27 (6) |
| 0.1 | 0.0034 ± 0.0009 (8) | 2.21 ± 1.23 (8) |
| 0.3 | 0.0036 ± 0.0009 (4) | 6.51 ± 2.26 (4) |
| 1 | 0.0042 ± 0.0018 (8) | 5.26 ± 2.13 (8) |
a
Multiplicity of infection (MOI) of HCMV strain AD169-GFP.
b
EC50values determined by the fluorescence reduction assay are expressed as means ± standard deviations. The number of independent experiments is shown in parentheses.