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Antibody responses to S. dysenteriae 1 LPS in cynomolgus macaques challenged intraduodenally with increasing doses of S. dysenteriae 1. Blood was collected 1 d before and at several times after challenge with the indicated inocula of S. dysenteriae 1, and (A) IgG and (B) IgA antibodies to S. dysenteriae 1 LPS were measured. The challenge strain used in monkey 15175 was isolated from the feces of monkey 2618M.
