Table 3.
Fecal shedding (+ or –) and clinical signs (score, 0 through 4) in macaques inoculated intragastrically with S. dysenteriae 1 (target inoculum, 1 × 1011cfu; actual inoculum, 1.05 × 1011cfu)
Days after challenge |
|||||||||||||||||||
1 |
2 |
3 |
4 |
5 |
6 |
7 |
12 |
||||||||||||
Monkey | am | pm | am | pm | am | pm | am | pm | |||||||||||
20546 | + | + | 2 | + | – | 0 | + | – | 2 | – | – | 2 | – | 0 | + | 0 | + | 0 | – |
19902 | – | – | 1 | + | – | 0 | + | + | 2 | + | – | 0 | + | 0 | + | 0 | – | 0 | – |
20539 | – | – | 1 | + | + | 0 | + | – | 2 | + | + | 0 | + | 0 | + | 0 | – | 0 | – |
Empty cell, data unavailable; ID, intraduodenally; IG, intragastrically; +, positive culture; –, no growth on culture; 0, no diarrhea; 1, soft formed stool; 2, diarrhea without blood (sometimes with mucus); 3, diarrhea with blood and mucus; 4, watery diarrhea with blood and mucus