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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Toxicol Mech Methods. 2010 Feb;20(2):53–58. doi: 10.3109/15376510903584677

Figure 2.

Figure 2

Rate of benzo(a)pyrene metabolism in adipose microsomes of ApcMin mice pre-exposed to benzo(a)pyrene. Explanations of the abbreviations are as follows; BaP-no pretr: BaP metabolite concentrations from microsomes of unexposed mice incubated with 3μM BaP alone; BaP + FL-no BaP pretr: BaP metabolite concentrations from microsomes of unexposed mice incubated with 3μM FLA + 3μM BaP; BaP-BaP pretr: BaP metabolite concentrations from microsomes of BaP (50 μg/kg)-pretreated mice incubated with 3μM of BaP alone; BaP + FLA-BaP pretr: BaP metabolite concentrations from microsomes of BaP (50 μg/kg)-pretreated mice incubated with 3μM each of BaP and FLA. Values are expressed as mean concentration of total metabolites ± SE. Data from triplicate determination (variability was <10%) of five individual animals from each treatment group were compared. Asterisks denote statistical significance (*** p < 0.001, ** p < 0.01) in BaP metabolite concentrations among the treatment categories.