Table 1.
Parameters | Controls (n = 53) | No ADT (n = 81) | Acute ADT (n = 43) | Chronic ADT (n = 67) | p-Value (across groups) |
---|---|---|---|---|---|
Age (years) | 62.55 ± 1.59 | 66.70 ± 0.81 | 70.86 ± 1.19 | 71.07 ± 1.07 | <0.0001 |
Duration of ADT (months) | 2.95 ± 0.25 | 30.67 ± 3.78 | |||
Body mass index (kg/m2) | 27.62 ± 0.47 | 28.26 ± 0.41 | 28.43 ± 0.88 | 29.12 ± 0.61 | 0.3352 |
Body fat (g) | 21629.25 ± 930.57 | 23606.34 ± 895.82 | 23999.39 ± 1240.08 | 27469.28 ± 1129.24 | 0.0013 |
Body fat % (% of total mass) | 25.14 ± 0.71 | 26.74 ± 0.66 | 27.08 ± 0.83 | 31.43 ± 0.65 | <0.0001 |
Lean body mass (g) | 60157.05 ± 884.79 | 60238.66 ± 771.04 | 59881.70 ± 1147.27 | 56482.19 ± 1014.13 | 0.0092 |
Lean body mass % (% of total mass) | 71.62 ± 0.67 | 70.25 ± 0.62 | 69.92 ± 0.79 | 65.86 ± 0.63 | <0.0001 |
Testosterone (ng/dl) | 421.88 ± 24.64 | 345.5 ± 18.90 | 81.69 ± 30.65 | 34.7 ± 12.87 | <0.0001 |
Free testosterone (pg/ml) | 66.47 ± 5.00 | 55.4 ± 3.21 | 11.64 ± 6.69 | 2.2 ± 0.38 | <0.0001 |
PSA (ng/ml) | 1.8 ± 0.2 | 1.6 ± 0.3 | 3.0 ± 1.2 | 6.2 ± 2.1 | 0.0219 |
Abbreviations: ADT, androgen deprivation therapy, PSA, prostate specific antigen.