Table 4.
Risk Factors for Pre-Transplant Mortality in HIV+ Transplant Candidates
| Univariate Analysis | ||||
|---|---|---|---|---|
| Risk Factor at Enrollment | Hazard for Death | Hazard for MELD >25 | ||
| MELD > 25 | HR = 15.0 | p<0.0001 | - | |
| HCV Co-Infection | HR = 1.0 | p = 0.97 | HR = 0.8 | p = 0.52 |
| Protease Inhibitor Regimen | HR = 1.5 | p = 0.37 | HR = 1.2 | p = 0.59 |
| CD4 < 200/μl | HR = 1.1 | p = 0.74 | HR = 1.0 | p = 0.94 |
| Detectable HIV RNA | HR = 3.2 | p = 0.02 | HR = 2.79 | p = 0.005 |
| Multivariate Analysis | ||
|---|---|---|
| Risk Factor at Enrollment | Hazard for Death | |
| MELD 15–19 | HR = 5.7 | p = 0.005 |
| MELD 20–24 | HR = 21.4 | p < 0.0001 |
| MELD ≥ 25 | HR = 101.1 | p < 0.0001 |
| CD4 < 200/μl | HR = 2.4 | p = 0.07 |
| Detectable HIV RNA | HR = 1.0 | p = 0.98 |