Table 1.
Body weights (BW), kidney weights (KW), and baseline kidney tissue pO2 in sham or rats with a silver clip placed on the renal artery of the left kidney (2K,1C) prior to the different acute interventions.
| KW/BW (x1000) |
Ratio Kidney Size (Clipped/Non-clipped) | Baseline Cortical pO2 (mmHg) | Baseline Medullary pO2 (mmHg) | |||||
|---|---|---|---|---|---|---|---|---|
| Type | Intervention | N | BW (g) | Non-clipped | Clipped | |||
| Sham | Candesartan and Candesartan + enalaprilat | 7 | 511±12 | - | 2.69±0.08 | - | 43±3 | 28±1 |
| Sham | Tempol and Tempol + enalaprilat | 7 | 492±16 | - | 2.65±0.09 | - | 47±2 | 28±2 |
| 2K,1C | Candesartan and Candesartan + enalaprilat | 8 | 466±23 | 5.43±0.39† | 3.55±0.63* | 0.64±0.08 | 42±3 | 16±2* |
| 2K,1C | Tempol and Tempol + enalaprilat | 7 | 477±7 | 6.45±0.41† | 4.53±0.30* | 0.70±0.02 | 41±1 | 14±1* |
All values are mean ± SEM.
*
denotes p<0.05 when compared to corresponding Sham group, and
†
denotes p<0.05 when compared to the clipped kidney within the same group.