Table 2.
Response in mean arterial blood pressure (MAP), relative cortical blood flow (CBF) and kidney pO2 to administration of the selective AT2-R blocker PD-123,319 and the combination of PD-123,319 + enalaprilat in a separate group of 2K,1C rats.
| Parameter | Baseline | After PD-123,319 | After PD-123,319 + enalaprilat |
|---|---|---|---|
| MAP (mmHg) | 162±5 | 155±5 | 133±5* |
| CBF (% of baseline) | 100 | 101±11 | 88±9 |
| Cortical pO2 (% of baseline) | 100 | 105±3.3 | 104±5 |
| Medullary pO2 (% of baseline) | 100 | 96±11 | 91±17 |
All values are mean ± SEM of n=7.
*
denotes p<0.05 when compared to baseline.