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Effect of overexpression of crmA and p35 on AIF translocation. In control cultures, OGD increased AIF translocation 100% (relative to normoxic/normoglycemic cultures expressing reporter gene), whereas overexpression of crmA or p35 entirely blocked AIF translocation (relative to normoxic/normoglycemic cultures expressing either crmA or p35). n=16 to 20
** p<0.01 as compared to normoxic/normoglycemic cells treated with βgal.
# p<0.05 as compared to βgal/OGD.
