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. Author manuscript; available in PMC: 2010 Feb 22.
Published in final edited form as: Blood. 2004 Oct 12;105(4):1807–1809. doi: 10.1182/blood-2004-02-0454

Figure 2. Alteration in the polysomal distribution of γ-globin mRNA in reticulocytes subsequent to butyrate therapy.

Figure 2

Before therapy (◆) and at 24 hours (■). Fractions 1 and 2 are the prepolysomal region; fractions 5 to 8, the 1 to 3 ribosomal region. (A) Analysis of γ-globin mRNA from reticulocytes from a representative patient with SCD responsive to butyrate. (B) Analysis of γ-globin mRNA from reticulocytes from another representative patient with SCD responsive to butyrate.