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. 2010 Jan 29;5:2. doi: 10.1186/1750-1172-5-2

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Copyright ©2010 Larizza et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Absolute number of tumours developed by RTS patients (X axis) grouped by the tissue of origin for each tumour type (Y axis): Among mesenchymal tumours, osteosarcoma (OS) is the most frequent. Several cases of multicentric osteosarcoma (OSMC) have been described, while malignant fibrous histiocytoma (MFH) has been reported in two cases. Squamous cell carcinoma (SCC) is the most frequent cutaneous epithelial tumour followed by basal cell carcinoma (BCC) and Bowen's disease (BD). Myelodysplasia has been reported in three cases (MD). Reports of single cases: fibrosarcoma* (FS), verrucous carcinoma (VC), Hodgkin's "sarcoma" (HS), acute myeloid leukaemia (AML), nasopharyngeal non-Hodgkin's lymphoma* (NPhNHL). The group other consists of single cases of gastric carcinoma, malignant eccrine poroma *, parathyroid adenoma *, amelanotic melanoma (41) (*all these were reported as a second neoplasia).