Table 2.
Genotype | Minimally adjusted model LSmean (95% CI) | Punadjusted | PFDR-adjusted | Fully adjusted model LSmean (95% CI) | Punadjusted | PFDR-adjusted |
---|---|---|---|---|---|---|
rs3093058 (CRP) | 0.0013 | 0.018 | 0.0012 | 0.023 | ||
TT | 0.45 (0.29,0.71) | 0.44 (0.29,0.66) | ||||
TA | 0.42 (0.37,0.49) | 0.41 (0.36,0.46) | ||||
AA | 0.32 (0.30,0.34) | 0.32 (0.31,0.33) | ||||
rs1205(CRP) | 0.0012 | 0.018 | 0.0059 | 0.038 | ||
AA | 0.28 (0.26,0.31) | 0.29 (0.27, 0.31) | ||||
AG | 0.32 (0.30,0.34) | 0.32 (0.31, 0.34) | ||||
GG | 0.34 (0.32,0.37) | 0.34 (0.32, 0.35) | ||||
rs1801131 (MTHFR) | 0.35 | 0.71 | 0.0024 | 0.023 | ||
TT | 0.33 (0.29,0.36) | 0.30 (0.28,0.32) | ||||
TC | 0.32 (0.30,0.34) | 0.32 (0.30,0.33) | ||||
CC | 0.33 (0.31,0.35) | 0.33 (0.32,0.35) | ||||
rs4994 (ADRB3) | 0.022 | 0.19 | 0.0026 | 0.023 | ||
CC | 0.29 (0.20,0.42) | 0.29 (0.23, 0.38) | ||||
CT | 0.29 (0.27,0.31) | 0.29 (0.28, 0.31) | ||||
TT | 0.33 (0.31,0.35) | 0.33 (0.31, 0.34) |
Note. *Only associations with unadjusted P (i.e., not adjusted for FDR) ≤ 0.05 in fully adjusted models are presented. FDR = false discovery rate.