Skip to main content
. 2010 Feb 23;5(2):e9378. doi: 10.1371/journal.pone.0009378

Table 1. The Sec7 family of the Dictyostelia.

Family Species Protein coding gene Gene ID Length (aa) Domains
GBF
D. d. DDB0233595 DDB_G0290771 1,748 Sec7
P. pallidum PPL_08838 871 Sec7
D. f. DFA_05701 1455 Sec7
BIG
D. d. DDB0233618 DDB_G0290369 1,886 Sec7, DUF1981
D. d. DDB0304853 DDB_G0290369 2,048 Sec7, DUF1981
D. d. DDB0233619 DDB_G0273831 2,048 Sec7, DUF1981
P. p. PPL_04049 1618 Sec7, DUF1981
P. p PPL_08053 1859 Sec7, DUF1981
D. f. DFA_04299 1956 Sec7, DUF1981
D. f. DFA_12170 1766 Sec7, DUF1981
Cytohesin
D. d. DDB0233591 DDB_G0279241 919 MFS, Sec7, PH
D. d. DDB0233617 DDB_G0272486 931 Sec7, PH
D. d. DDB0191439 DDB_G0287459 986 Ankyrin, Sec7, PH
P. p. PPL_10293 686 TM, Sec7, PH
P. p. PPL_12526 971 Sec7, PH
P. p. PPL_05633 1696 Ankyrin, Sec7, PH, Zn2+finger
D. f. DFA_11559 678 DUF2339 Sec7, PH
D. f. DFA_11731 866 Sec7, PH
D. f: DFA_04214 962 Ankyrin, Sec7, PH

The Sec7 family members in three taxonomic divisions of the Dictyostelia are listed. The D. discoideum genome [11] was searched for proteins containing a Sec7 domain (dictyBase, http://dictybase.org/index.html). The families were classified according to Casanova [46]. The domains listed were identified by Blast searches (http://blast.ncbi.nlm.nih.gov/Blast.cgi). The D. discoideum (D. d.) proteins were then used to search for homologues in the D. falciparum (D. f.) and P. pallidum (P. p.) genomes at http://sacgb.fli-leibniz.de/cgi/index.pl. D. falciparum belongs to group 1, P. pallidum is a member of group 2 and D. discoideum (D. d.) is a member of group 4. The homology search was done by Blast. DUF1981, DUF2339, domains of unknown function, present in predicted membrane proteins. MFS, Major-Facilitator-Superfamily, group of membrane proteins; TM, transmembrane; DUF1981, domain of unknown function, present in predicted membrane proteins, PH, PH-domain.