Table 1. The Sec7 family of the Dictyostelia.
Family | Species | Protein coding gene | Gene ID | Length (aa) | Domains |
GBF | |||||
D. d. | DDB0233595 | DDB_G0290771 | 1,748 | Sec7 | |
P. pallidum | PPL_08838 | 871 | Sec7 | ||
D. f. | DFA_05701 | 1455 | Sec7 | ||
BIG | |||||
D. d. | DDB0233618 | DDB_G0290369 | 1,886 | Sec7, DUF1981 | |
D. d. | DDB0304853 | DDB_G0290369 | 2,048 | Sec7, DUF1981 | |
D. d. | DDB0233619 | DDB_G0273831 | 2,048 | Sec7, DUF1981 | |
P. p. | PPL_04049 | 1618 | Sec7, DUF1981 | ||
P. p | PPL_08053 | 1859 | Sec7, DUF1981 | ||
D. f. | DFA_04299 | 1956 | Sec7, DUF1981 | ||
D. f. | DFA_12170 | 1766 | Sec7, DUF1981 | ||
Cytohesin | |||||
D. d. | DDB0233591 | DDB_G0279241 | 919 | MFS, Sec7, PH | |
D. d. | DDB0233617 | DDB_G0272486 | 931 | Sec7, PH | |
D. d. | DDB0191439 | DDB_G0287459 | 986 | Ankyrin, Sec7, PH | |
P. p. | PPL_10293 | 686 | TM, Sec7, PH | ||
P. p. | PPL_12526 | 971 | Sec7, PH | ||
P. p. | PPL_05633 | 1696 | Ankyrin, Sec7, PH, Zn2+finger | ||
D. f. | DFA_11559 | 678 | DUF2339 Sec7, PH | ||
D. f. | DFA_11731 | 866 | Sec7, PH | ||
D. f: | DFA_04214 | 962 | Ankyrin, Sec7, PH |
The Sec7 family members in three taxonomic divisions of the Dictyostelia are listed. The D. discoideum genome [11] was searched for proteins containing a Sec7 domain (dictyBase, http://dictybase.org/index.html). The families were classified according to Casanova [46]. The domains listed were identified by Blast searches (http://blast.ncbi.nlm.nih.gov/Blast.cgi). The D. discoideum (D. d.) proteins were then used to search for homologues in the D. falciparum (D. f.) and P. pallidum (P. p.) genomes at http://sacgb.fli-leibniz.de/cgi/index.pl. D. falciparum belongs to group 1, P. pallidum is a member of group 2 and D. discoideum (D. d.) is a member of group 4. The homology search was done by Blast. DUF1981, DUF2339, domains of unknown function, present in predicted membrane proteins. MFS, Major-Facilitator-Superfamily, group of membrane proteins; TM, transmembrane; DUF1981, domain of unknown function, present in predicted membrane proteins, PH, PH-domain.