Table 3.
Cross-sectional analyses (odds of prevalent disease with antihypertensive medication use)
| Antihypertensive agent | Essential tremor | Parkinson's disease | Dementia |
|---|---|---|---|
| Any antihypertensive agent | 1.28 (0.995–1.64), 0.055 | 1.28 (0.83–1.99), 0.27 | 0.93 (0.73–1.17), 0.53 |
| 1.15 (0.88–1.50), 0.32 | 1.17 (0.74–1.86), 0.50 | 0.88 (0.66–1.16), 0.36 | |
|
| |||
| Any antihypertensive agent (excluding β-blockers) | 1.21 (0.94–1.56), 0.14 | 1.17 (0.75–1.81), 0.49 | 0.97 (0.77–1.23), 0.81 |
| 1.09 (0.83–1.42), 0.54 | 1.05 (0.66–1.66), 0.84 | 0.89 (0.67–1.19), 0.43 | |
|
| |||
| Calcium channel blockers | 0.97 (0.64–1.45), 0.87 | 1.30 (0.68–2.46), 0.43 | 0.65 (0.42–1.01), 0.06 |
| 0.87 (0.57–1.33), 0.52 | 1.13 (0.59–2.17), 0.71 | 0.63 (0.39–1.01), 0.06 | |
In logistic regression models, use of an antihypertensive agent was the independent variable, and diagnosis (essential tremor, Parkinson's disease, dementia, in different models) was the dependent variable. Unadjusted models are reported (upper row in each cell) and then models that adjusted for age, gender, education and self-reported depression (lower row in each cell). Results are given as OR (95% CI) and p values. For any antihypertensive agent, the attributable risk was: −1.1% (essential tremor); 0.4% (Parkinson's disease), and −0.4% (dementia).