(A) Intracellular cAMP levels of cells in control, 0.2 mM palmitatate (0.2-P), 0.4 mM palmitatate (0.4-P), 0.7 mM palmitatate (0.7-P), 0.7 mM oleate (0.7-O) and 0.7 mM linoleate (0.7-L) for 24 hrs (n=4). (B) Intracellular cAMP levels of cells in control, 0.7 mM palmitatate (P), 0.7 mM palmitatate supplemented with 100 μM IBMX (P+I), 0.7 mM palmitatate supplemented with 1 μM forskolin (P+F), 0.7 mM palmitatate supplemented with 1 μM 8CPT-2Me-cAMP (P+8CPT), 0.7 mM palmitatate supplemented with 100 nM glucagon (P+G) and 0.7 mM palmitatate supplemented with 10 μM forskolin and 100 μM IBMX (P+FI) for 24 hrs (n=3). *: p<0.05; **: p<0.01; ***: p<0.001.