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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Cell Signal. 2010 Jan 11;22(5):749–758. doi: 10.1016/j.cellsig.2009.12.010

Figure 5.

Figure 5

Effect of simvastatin on expression of PTEN. (A) MDA-MB-231 breast cancer cells were incubated with 10 μM simvastatin for 24 hours. The cell lysates were immunoblotted with anti-PTEN and anti-tubulin antibodies as indicated. (B) Tumor lysates from independent control and independent simvastatin-treated mice were immunoblotted with PTEN and actin antibodies respectively. (C) Quantification of PTEN expression in panel B. Mean ± SE of four independent animals is shown. *p < 0.01 vs. control.