Figure 2.
Flowchart of the gene-based combined odds ratio (OR) methods for weighting evidence for schizophrenia candidate gene selection. OR is the ratio of allele carriers to non-carriers in cases compared with that in controls. In the figure, there are two alternative approaches to selecting representative OR of a study: selection (the largest OR value of all the markers being selected, step one in the SCOR method) and combination (the OR values of all markers being combined by the “meta” analysis, step one in the CCOR method).