Figure 5.
(A) The catalytic antioxidant MnTDE-1,3-IP5+ (MnP, 5 μM) protected A549 cells against Cas IIgly-induced injury (7.5 μM, 24 h treatment). (B) H157 cells required higher amounts of MnTDE-1,3-IP5+ (MnP, 20 μM) to protect against Cas IIgly-induced injury (5 μM). Membrane integrity (percentage of LDH release) was used as an index of cytotoxicity. Bars with different letters are statistically different from one another (n = 3, P < 0.05).