Table 1.
Asthma | Healthy | |||||
---|---|---|---|---|---|---|
% | M | SD | % | M | SD | |
Age (range 10-20 yearsa) | 15.0 | 2.8 | 15.9 | 2.0 | ||
Gender (% male) | 68 | 57 | ||||
Ethnicity | ||||||
Caucasian | 58 | |||||
Asian | 26 | 17 | ||||
Other | 16 | 9 | ||||
Severity | ||||||
Mild intermittent | 13 | |||||
Mild persistent | 45 | |||||
Moderate persistent | 29 | |||||
Severe | 13 | |||||
Atopic | 55 | 13 | ||||
FEV1/FVC | .76 | .12 | .84 | .08 | ||
ICSa | 6.0 | 6.3 | 0 | 0 | ||
ICS dose | ||||||
Low | 73 | |||||
Medium | 27 | |||||
High | 0 | |||||
Beta agonistsb | 5.1 | 6.2 | 0 | 0 | ||
Baseline FEV1% | 90.6 | 16.6 | 99.0 | 8.4 | ||
Post-task FEV1% | 90.0 | 14.1 | 97.0 | 9.1 | ||
Baseline FeNO (ppb) | 58.5 | 57.5 | 22.8 | 24.4 | ||
Post-task FeNO (ppb) | 53.5 | 51.5 | 21.4 | 23.5 |
ICS=inhaled corticosteroids. FEV1%= forced expiratory volume in 1 second percent predicted. FeNO= fractional concentration of exhaled nitric oxide in parts per billion. FEV1/FVC=ratio of FEV1 to forced vital capacity.
age range for asthma group: 10-20 years; age range for healthy group: 11-18 years.
=number of days taken in previous 2 weeks, range for both medications in the asthma group was from 0 to 14 days.