Table 1.
Clinical, operative and pathological characteristics with respect to tumour burden
| Prognostic factors |
Tumour burden |
P-value | ||
|---|---|---|---|---|
| Low (n= 154) | Moderate (n= 262) | High (n= 289) | ||
| Age (years) | ||||
| <65 | 74 (48.1%) | 140 (53.4%) | 148 (51.2%) | 0.569 |
| ≥65 | 80 (51.9%) | 122 (46.6%) | 141 (48.8%) | |
| Gender | ||||
| Male | 92 (59.7%) | 167 (63.7%) | 187 (64.7%) | 0.575 |
| Female | 62 (40.3%) | 95 (36.3%) | 102 (35.3%) | |
| Presentation | ||||
| Synchronous | 60 (39.0%) | 99 (37.8%) | 139 (48.1%) | 0.164 |
| Metachronous | 94 (61.0%) | 163 (62.2%) | 150 (51.9%) | |
| IRT* | ||||
| Yes | 16 (14.0%) | 33 (16.3%) | 67 (29.5%) | <0.001 |
| No | 98 (86.0%) | 169 (83.7%) | 160 (70.5%) | |
| Extent of resection | ||||
| Less than hemi-hepatectomy | 102 (66.2%) | 100 (38.2%) | 61 (21.1%) | <0.001 |
| Hemi-hepatectomy or more | 52 (33.8%) | 162 (61.8%) | 228 (78.9%) | |
| Blood transfusion | 32 (20.8%) | 61 (23.3%) | 56 (19.4%) | 0.529 |
| Morbidity | 59 (38.3%) | 102 (38.9%) | 130 (45.0%) | 0.248 |
| Resection margin | ||||
| R1 (Involved) | 35 (22.7%) | 83 (31.7%) | 140 (48.4%) | <0.001 |
| R0 (≥1 mm) | 119 (77.3%) | 179 (68.3%) | 149 (51.6%) | |
*
IRT was available in 543 (77.0%) patients, with 114 (74.0%), 202 (77.1%) and 227 (78.5%) patients, respectively, in the low, moderate and high tumour burden groups.