Table 3.

Statistical analysis of prognostic factors with respect to disease-free survival

Prognostic factors for disease-free survival	Univariate analysis	Multivariate analysis	Hazard Ratios	Confidence Interval
Age ≥65 years (n= 343, 48.7%)	0.324	NA	NA	NA
Female gender (n= 259, 36.7%)	0.956	NA	NA	NA
Synchronous presentation (n= 298, 42.3%)	0.331	NA	NA	NA
IRT (n= 116, 21.4%)*	<0.001	<0.001	1.551	1.217–1.975
Hemi-hepatectomy or more (n= 442, 62.7%)	0.046	0.413	0.901	0.701–1.157
Blood transfusion (n= 149, 21.1%)	0.007	0.002	1.473	1.155–1.877
High tumour burden (n= 289, 41%)	<0.001	0.023	1.205	1.026–1.416
R1 margin (n= 258, 36.6%)	<0.001	0.001	1.487	1.185–1.865

NA, not applicable; IRT, inflammatory response to tumour.

^*IRT was available in 543 (77.0%) patients.