Table 1.
Kinetics of CD8+ cell proliferation induced by different splenic dendritic cells
| Percentage of among CD8+ T cells1,2 |
||||||||
|---|---|---|---|---|---|---|---|---|
| Without CD4+ T cells |
With CD4+ T cells |
|||||||
| Time (hr) | LPS | LNFPIII | has | Media | LPS | LNFPIII | HSA | Media |
| 24 | 7·6 ± 2·2 | 7·3 ± 3·2 | 8·0 ± 3·9 | 7·5 ± 3·2 | 21·1 ± 1·8* | 20·6 ± 1·6* | 11·0 ± 1·7 | 9·3 ± 0·9 |
| 48 | 26·8 ± 1·6** | 28·5 ± 1·9** | 10·7 ± 1·9 | 7·2 ± 3·0 | 55·0 ± 5·4** | 46·4 ± 2·8** | 17·8 ± 2·4 | 14·7 ± 1·6 |
| 72 | 53·3 ± 6·7** | 51·8 ± 5·5** | 32·4 ± 8·3 | 33·0 ± 7·4 | 83·1 ± 2·5** | 82·0 ± 2·8** | 36·8 ± 4·9 | 32·6 ± 5·2 |
1
Percentages of proliferating cell populations among CD8+ T cells are presented as mean ± SD (n = 6).
2
Experiments were performed twice with similar results.
*
P< 0·05,
**
P< 0·01 when compared with control groups.
HSA, human serum albumin; LNFPIII, lacto-N-fucopentaose III; LPS, lipopolysaccharide.