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. Author manuscript; available in PMC: 2010 Feb 23.
Published in final edited form as: Am J Immunol. 2009 Jan 1;5(3):65–83. doi: 10.3844/ajisp.2009.65.83

Figure 1. Target lymphocyte populations of gamma(c) cytokines.

Figure 1

While there is considerable overlap of cytokine activity on lymphocytes, effects can be stimulatory or inhibitory depending on the cytokine. IL-21 only increases proliferation of T cells stimulated with anti-CD3 or antigen, but can augment responses to other gamma(c) cytokines. IL-7 acts on developing B cells but not mature cells of this lineage. IL = interleukin, NK = natural killer, NKT = natural killer-T cell, Treg = regulatory T cell