Table 2.

Acute mechanical and thermal sensitivity in WT and Nt5e^−/− mice

Behavioral assay	Withdrawal threshold (g) or latency (s)
	Wild-type	Nt5e−/−
Electronic von Frey	8.1 ± 0.2 g	7.7 ± 0.2 g
Radiant heating of hindpaw (Hargreaves method)	10.6 ± 0.3 s	10.3 ± 0.4 s
Tail immersion at 46.5°C	13.8 ± 1.1 s	9.5 ± 0.5 s**
Tail immersion at 49.0°C	5.6 ± 0.3 s	4.2 ± 0.2 s**
Hot plate at 52°C	29.4 ± 2.1 s	31.4 ± 2.7 s

n = 10 male mice tested per genotype. Data are expressed as means ± SEM. Paired t test was used to compare genotypes for each test,

**p < 0.005.