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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Front Biosci (Elite Ed). 2010 Jan 1;2:495–503. doi: 10.2741/e108

Figure 1.

Figure 1

Effects of knockout of AT1A receptor gene (AT1A-KO) on the cold-induced increase in cardiac endothelin-1 production. The measurement was done in mice expose to cold (5°C) for 5 weeks. AT1A-KO-Cold, AT1A-KO mice exposed to cold (5±2°C); AT1A-KO-Warm, AT1A-KO mice maintained at room temperatures (warm, 25±2°C); WT-Cold, wild type mice maintained at cold; WT-Warm, wild type mice maintained at room temperatures (warm). ***p<0.001 vs the WT-Warm group. N=6.